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Advances in IgA Nephropathy:

What Clinicians Need to Know Now

Activity 2

Mechanisms Behind the Pathogenesis of IgAN:

The 4-Hit Hypothesis

Learning Objective: Connect IgAN pathogenesis to the mechanisms of action of new and emerging therapies​

 

5-minute medical animation and “Test Your Knowledge” question with Dana V. Rizk, MD, Professor of Medicine, Division of Nephrology, University of Alabama at Birmingham in the United States

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Pre-Hit 1: The Role of APRIL and BAFF in B-Cell Activation and Gd-IgA1 Production

Learning Objective: Connect IgAN pathogenesis to the mechanisms of action of new and emerging therapies​

3-minute medical animation and “Test Your Knowledge” question with Jonathan Barratt, PhD, FRCP, Professor of Renal Medicine at the University of Leicester in the United Kingdom.

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Therapeutic Advances in IgA Nephropathy

Learning Objective: Recognize how new treatment strategies can overcome limitations of conventional approaches to immunosuppression

49-minute presentation with Dana V. Rizk, MD and Jonathan Barratt, PhD, FRCP.

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